Madrid (MAD) to Panama City (PTY) flight deal in business from $2,239

AeroméxicoAMAeroméxico
Round Trip•Business Class
SpainMAD

Madrid-Barajas Airport

Madrid, Spain
PanamaPTY

Tocumen International Airport

Panama City, Panama
$5,255 USD
-57%$2,239 USD
Verified 13 days ago
Extremely Rare Availability
4% of dates checked are available within 10% of the lowest price

Monday, December 21st, 2026

3 round-trip options

Returning
Sun, Dec 27, 2026•6 Day Trip
$3,609 USD
Google Flights
Returning
Wed, Dec 30, 2026•9 Day Trip
$2,376 USD
Google Flights
Returning
Fri, Jan 1, 2027•11 Day Trip
$2,547 USD
Google Flights