Madrid (MAD) to Panama City (PTY) flight deal in business from $2,239

AeroméxicoAMAeroméxico
Round Trip•Business Class
SpainMAD

Madrid-Barajas Airport

Madrid, Spain
PanamaPTY

Tocumen International Airport

Panama City, Panama
$5,255 USD
-57%$2,239 USD
Verified 13 days ago
Extremely Rare Availability
4% of dates checked are available within 10% of the lowest price

Saturday, December 19th, 2026

5 round-trip options

Returning
Fri, Dec 25, 2026•6 Day Trip
$4,703 USD
Google Flights
Returning
Mon, Dec 28, 2026•9 Day Trip
$4,532 USD
Google Flights
Returning
Tue, Dec 29, 2026•10 Day Trip
$4,532 USD
Google Flights
Returning
Wed, Dec 30, 2026•11 Day Trip
$4,532 USD
Google Flights
Returning
Thu, Dec 31, 2026•12 Day Trip
$6,516 USD
Google Flights