Madrid (MAD) to Panama City (PTY) flight deal in business from $2,239

AeroméxicoAMAeroméxico
Round Trip•Business Class
SpainMAD

Madrid-Barajas Airport

Madrid, Spain
PanamaPTY

Tocumen International Airport

Panama City, Panama
$5,255 USD
-57%$2,239 USD
Verified 13 days ago
Extremely Rare Availability
4% of dates checked are available within 10% of the lowest price

Sunday, December 6th, 2026

5 round-trip options

Returning
Sat, Dec 12, 2026•6 Day Trip
$5,131 USD
Google Flights
Returning
Tue, Dec 15, 2026•9 Day Trip
$6,516 USD
Google Flights
Returning
Wed, Dec 16, 2026•10 Day Trip
$6,516 USD
Google Flights
Returning
Thu, Dec 17, 2026•11 Day Trip
$6,516 USD
Google Flights
Returning
Fri, Dec 18, 2026•12 Day Trip
$6,688 USD
Google Flights