Madrid (MAD) to Panama City (PTY) flight deal in business from $2,239

AeroméxicoAMAeroméxico
Round Trip•Business Class
SpainMAD

Madrid-Barajas Airport

Madrid, Spain
PanamaPTY

Tocumen International Airport

Panama City, Panama
$5,255 USD
-57%$2,239 USD
Verified 13 days ago
Extremely Rare Availability
4% of dates checked are available within 10% of the lowest price

Wednesday, December 16th, 2026

5 round-trip options

Returning
Tue, Dec 22, 2026•6 Day Trip
$4,360 USD
Google Flights
Returning
Fri, Dec 25, 2026•9 Day Trip
$6,517 USD
Google Flights
Returning
Sat, Dec 26, 2026•10 Day Trip
$5,765 USD
Google Flights
Returning
Sun, Dec 27, 2026•11 Day Trip
$5,593 USD
Google Flights
Returning
Mon, Dec 28, 2026•12 Day Trip
$4,362 USD
Google Flights